Weekly Chest CasesArchive of Old Cases

Case No : 230 Date 2002-03-23

  • Courtesy of Joon Beom Seo, M.D., Jin Seong Lee, M.D., Koun-Sik Song, M.D. / Asan Medical Center, Seoul, Korea
  • Age/Sex 60 / M
  • Chief ComplaintDyspnea for several months
  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4

Diagnosis With Brief Discussion

Diagnosis
Bronchiolitis Obliterans Organizing Pneumonia
Radiologic Findings
PA chest radiograph shows bilateral areas of consolidation, predominantly in lower lung zones. Thin-section CT scans show patchy areas of consolidation and ground-glass opacity in both lungs.Predominant lower lung zone, subpleural, peribronchial distribution of the lesions is noted.

Open lung biopsy revealed multipel granulation polyps filling respiratiory bronchioles and alveolar ducts and bronchial wall thickening, consistent with broncholitis obliterans organizing pneumonia.
Brief Review
Histology
Granulation tissue polyps within respiratory bronchioles and alveolar ducts (Masson bodies) associated with patchy orgainzing pneumonia

Symptom
nonproductive cough, low-grade fever, shortness of breath

CT findings
Major
Pathcy bilateral airspace consolidation (80%)
Ground-glass opacity (60%)
Subpleural and/or peribronchovascular distribution
Minor
Bronchial wall thickening, dilatation
Small nodular opacities
Large nodules
Pleural effusion
Honeycombing (uncommon)
References
Keywords

No. of Applicants : 19

▶ Correct Answer : 17/19,  89.5%
  • - Busan Moonhwa hospital, Korea Yoo Kyung Kim
  • - Choong-ju Hospital Konkuk University, Korea Chang Hee Lee
  • - CHU Nancy-Brabois, France Denis Regent
  • - Daejeon Sun Hospital, Korea Dong Jip Na
  • - Ewha Womans' University, Mokdong Hospital, Korea Kyung Soo Cho
  • - Gochang Hospital, Korea Jiyong Rhee
  • - Harasanshin hospital, Fukuoka, Japan Shunya Sunami
  • - Inha hospital, Sungnam, Korea Sung Su Byun
  • - Inha University Hospital, Korea Dong-Jae Shim
  • - Korea Cancer Center Hospital, Korea Donghee Park
  • - Masan Yeonse Hospital, Korea Sang Hee Lee
  • - Ospedale di Jesi, Italy Giancarlo Passarini
  • - Samsung Medical Center, Korea Young Cheol Yoon
  • - Sctimst, Trivandrum, India Vilvendhan Rajendran
  • - Stedelijk OLV Ziekenhuis Mechelen, Belgium Ivan Pilate
  • - Sungji Hospital, Korea Jung Hee Kim
  • - Xray Clinic, Pune, India M D Rahalkar
▶ Semi-Correct Answer : 2/19,  10.5%
  • - Wallaece Memorial Baptist Hospital, Korea Mi ok Sunwoo
  • - Tae Kyun Jung
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